Who was studied 18,833 East Asian ancestry cases, 146,214 East Asian ancestry controls.
The effect
Each copy of the C allele shifted the measure 0.199 lower (95% confidence interval 0.14-0.25); p = 2 × 10−12.
How common The C allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 13, band 13q12.3 — in an intron of FLT1.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Stable angina pectoris — no copies of the reported risk allele.
A/CPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Stable angina pectoris.
C/CPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Stable angina pectoris compared to the general population.
rs75419986 is a single position in the genome, in or near the FLT1 gene. Published research associates it with stable angina pectoris. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75419986 linked to?
On MyGeneLog this position is linked to Colon Polyp. The research behind each link, and its sources, are set out on that condition page.
Does having rs75419986 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75419986 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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