Standard
Insulin-like growth factor 1 levels
ACTN4 · rs75403087
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Insulin-like growth factor 1 levels compared to the general population.
A/G
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Insulin-like growth factor 1 levels.
G/G
Published research associates this genotype with typical/baseline likelihood of Insulin-like growth factor 1 levels — no copies of the reported risk allele.
Source
Genetics of 35 blood and urine biomarkers in the UK Biobank
Sinnott-Armstrong N,
Tanigawa Y,
Amar D,
Mars N,
Benner C,
Aguirre M,
Venkataraman GR,
Wainberg M,
Ollila HM,
Kiiskinen T,
Havulinna AS,
Pirruccello JP
and 11 more — show all
Qian J,
Shcherbina A,
Rodriguez F,
Assimes TL,
Agarwala V,
Tibshirani R,
Hastie T,
Ripatti S,
Pritchard JK,
Daly MJ,
Rivas MA
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs75403087
What is rs75403087?
rs75403087 is a single position in the genome, in or near the ACTN4 gene. Published research associates it with insulin-like growth factor 1 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs75403087 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75403087 come from?
GWAS Catalog, Nat Genet 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants