Sensitive

Lung cancer

MIPEP · rs753955

Where this position leads

Condition: Lung Cancer

rs753955 Condition: Lung Cancer Lung Cancer Condition rs753955 rs753955 MIPEP

What the study found

Who was studied 2,331 Han Chinese ancestry cases, 3,077 Han Chinese ancestry controls; replicated in 6,313 Han Chinese ancestry cases, 6,409 Han Chinese ancestry controls.

The effect Each copy of the G allele carried 1.18 times the odds of Lung cancer (95% confidence interval 1.13-1.24); p = 2 × 10−12.

How common The G allele had a frequency of about 29% in the people studied.

Where it sits Chromosome 13, band 13q12.12 — between genes, 10.5 kb from MIPEP.

What each result means

A/A No copy of the version the research linked to Lung cancer. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Lung cancer. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Lung cancer. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs753955

What is rs753955?

rs753955 is a single position in the genome, in or near the MIPEP gene. Published research associates it with lung cancer. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs753955 linked to?

On MyGeneLog this position is linked to Lung Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs753955 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs753955 come from?

GWAS Catalog, Nature genetics 2011, PMID:21725308. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Lung cancer (rs753955). MyGeneLog™. https://www.mygenelog.com/variants/rs753955

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