A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Basal cell carcinoma compared to the general population. (GWAS Catalog, Nat Commun 2015, PMID:25855136)
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Basal cell carcinoma. (GWAS Catalog, Nat Commun 2015, PMID:25855136)
G/GPublished research associates this genotype with typical/baseline likelihood of Basal cell carcinoma — no copies of the reported risk allele. (GWAS Catalog, Nat Commun 2015, PMID:25855136)
rs7538876 is a single position in the genome, in or near the RCC2 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7538876 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs7538876 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7538876 come from?
GWAS Catalog, Nat Commun 2015, PMID:25855136. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.