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The effect
Each copy of the C allele shifted the measure 0.0359 higher (95% confidence interval 0.027-0.045); p = 1 × 10−14.
How common The C allele had a frequency of about 12% in the people studied.
Where it sits Chromosome 1, band 1q32.1 — in an intron of MIR181A1HG.
What each result means
C/CTwo copies of the version the research linked to Male-pattern baldness. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Male-pattern baldness. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Male-pattern baldness. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 30573740 · open access
Questions about rs7538393
What is rs7538393?
rs7538393 is a single position in the genome, in or near the near PTPRC gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7538393 linked to?
On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.
Does having rs7538393 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7538393 come from?
GWAS Catalog, Nat Commun 2018, PMID:30573740. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 172112218Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total17Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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