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Vertical cup-disc ratio

near WDR82P2 · rs7536573

What the study found

Who was studied 65,680 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.00505 higher (95% confidence interval 0.0036-0.0065); p = 2 × 10−15.

How common The C allele had a frequency of about 68% in the people studied.

Where it sits Chromosome 1, band 1p22.1 — between genes, 29.8 kb from WDR82P2.

What each result means

A/A No copy of the version the research linked to Vertical cup-disc ratio. This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Vertical cup-disc ratio. That is a smaller link than two copies.
C/C Two copies of the version the research linked to Vertical cup-disc ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7536573

What is rs7536573?

rs7536573 is a single position in the genome, in or near the near WDR82P2 gene. Published research associates it with vertical cup-disc ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7536573 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7536573 come from?

GWAS Catalog, American journal of human genetics 2021, PMID:34077760. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Vertical cup-disc ratio (rs7536573). MyGeneLog™. https://www.mygenelog.com/variants/rs7536573

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