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Who was studied 16,491 European ancestry cases, 1,202,106 European ancestry controls, 5,051 East Asian ancestry cases, 185,362 East Asian ancestry controls, 740 African American or Afro-Caribbean cases, 120,993 African American or Afro-Caribbean controls, 212 Hispanic or Latin American cases, 59,641 Hispanic or Latin American controls.
The effect
Each copy of the G allele shifted the measure 0.123 lower (95% confidence interval 0.074-0.172); p = 2 × 10−10.
Where it sits Chromosome 1, band 1p36.33 — inside SDF4.
What each result means
A/ANo copy of the version the research linked to Systemic lupus erythematosus. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Systemic lupus erythematosus. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Systemic lupus erythematosus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Mammalian genome : official journal of the International Mammalian Genome Society · 2026 · PMID 42581184
Questions about rs7536250
What is rs7536250?
rs7536250 is a single position in the genome, in or near the SDF4 gene. Published research associates it with systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7536250 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs7536250 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7536250 come from?
GWAS Catalog, Mammalian genome : official journal of the International Mammalian Genome Society 2026, PMID:42581184. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 00Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others0Total0Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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