Pediatric areal bone mineral density (concordant skeletal phenotype)
ZMAT4 · rs75321045
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 470 European ancestry females, 463 European ancestry males, 256 African and Asian ancestry females, 210 African and Asian ancestry males; replicated in 238 European ancestry females, 246 European ancestry males.
The effect
Each copy of the G allele shifted the measure 0.61 higher (95% confidence interval 0.39-0.83); p = 3 × 10−8.
How common The G allele had a frequency of about 95% in the people studied.
Where it sits Chromosome 8, band 8p11.21 — in an intron of ZMAT4.
What each result means
G/GTwo copies of the version the research linked to Pediatric areal bone mineral density (concordant skeletal phenotype). That is the strongest link of the three results. A link in a study is not a diagnosis.
G/TOne copy of the version the research linked to Pediatric areal bone mineral density (concordant skeletal phenotype). That is a smaller link than two copies.
T/TNo copy of the version the research linked to Pediatric areal bone mineral density (concordant skeletal phenotype). This is the starting point the study compared everyone against.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research · 2018 · PMID 29240982
Questions about rs75321045
What is rs75321045?
rs75321045 is a single position in the genome, in or near the ZMAT4 gene. Published research associates it with pediatric areal bone mineral density (concordant skeletal phenotype). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs75321045 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75321045 come from?
GWAS Catalog, J Bone Miner Res 2017, PMID:29240982. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 19281224Reads by AI crawlersClaude0ChatGPT2Google · Gemini0Perplexity0Meta AI8Microsoft · Copilot1Amazon2Apple2China (ByteDance, Huawei, Baidu…)0Others4Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Pediatric areal bone mineral density (concordant skeletal phenotype) (rs75321045). MyGeneLog™. https://www.mygenelog.com/variants/rs75321045