Standard

Systolic blood pressure

RYK · rs75305034

Where this position leads

Condition: Blood Pressure

rs75305034 Condition: Blood Pressure Blood Pressure Condition rs75305034 rs75305034 RYK

What the study found

Who was studied 295,529 European ancestry individuals, 8,231 Latino individuals, 3,058 African American individuals, 2,029 African British individuals, 7,701 East Asian ancestry individuals, 2,735 South Asian ancestry individuals, 1,979 mixed and unknown ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.331 higher; p = 3 × 10−10.

Where it sits Chromosome 3, band 3q22.2 — in an intron of RYK.

What each result means

C/C No copy of the version the research linked to Systolic blood pressure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Systolic blood pressure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Systolic blood pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75305034

What is rs75305034?

rs75305034 is a single position in the genome, in or near the RYK gene. Published research associates it with systolic blood pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75305034 linked to?

On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.

Does having rs75305034 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75305034 come from?

GWAS Catalog, Nat Genet 2016, PMID:27841878. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Systolic blood pressure (rs75305034). MyGeneLog™. https://www.mygenelog.com/variants/rs75305034

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