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White blood cell count (neutrophil)

near ATF6 · rs7529274

What the study found

Who was studied 21,347 Hispanic or Latin American individuals.

The effect Each copy of the A allele shifted the measure 0.0959 lower (95% confidence interval 0.068-0.124); p = 1 × 10−11.

How common The A allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 1, band 1q23.3 — between genes, 0.8 kb from ATF6.

What each result means

A/A Two copies of the version the research linked to White blood cell count (neutrophil). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to White blood cell count (neutrophil). That is a smaller link than two copies.
G/G No copy of the version the research linked to White blood cell count (neutrophil). This is the starting point the study compared everyone against.
Source

Questions about rs7529274

What is rs7529274?

rs7529274 is a single position in the genome, in or near the near ATF6 gene. Published research associates it with white blood cell count (neutrophil). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7529274 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7529274 come from?

GWAS Catalog, BMC genomics 2021, PMID:34107879. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

White blood cell count (neutrophil) (rs7529274). MyGeneLog™. https://www.mygenelog.com/variants/rs7529274

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