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Pancreas proton density fat fraction

TM4SF4 · rs75287519

What the study found

Who was studied 37,589 British ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.04 higher (95% confidence interval 0.02-0.06); p = 3 × 10−8.

How common The T allele had a frequency of about 52% in the people studied.

Where it sits Chromosome 3, band 3q25.1 — in an intron of TM4SF4.

What each result means

A/A No copy of the version the research linked to Pancreas proton density fat fraction. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Pancreas proton density fat fraction. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Pancreas proton density fat fraction. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75287519

What is rs75287519?

rs75287519 is a single position in the genome, in or near the TM4SF4 gene. Published research associates it with pancreas proton density fat fraction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75287519 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75287519 come from?

GWAS Catalog, Journal of obesity 2025, PMID:40922984. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Pancreas proton density fat fraction (rs75287519). MyGeneLog™. https://www.mygenelog.com/variants/rs75287519

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