Sensitive

Schizophrenia

HHAT · rs7527939

Where this position leads

Condition: Schizophrenia

rs7527939 Condition: Schizophrenia Schizophrenia Condition rs7527939 rs7527939 HHAT

What the study found

Who was studied 188 European ancestry cases, 376 European ancestry controls; replicated in 99 European ancestry cases, 328 European ancestry controls.

The effect Each copy of the C allele carried 2.63 times the odds of Schizophrenia (95% confidence interval 1.89-3.66); p = 6 × 10−9.

Where it sits Chromosome 1, band 1q32.2 — in an intron of HHAT.

What each result means

C/C Two copies of the version the research linked to Schizophrenia. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Schizophrenia. That is a smaller link than two copies.
T/T No copy of the version the research linked to Schizophrenia. This is the starting point the study compared everyone against.
Source

Questions about rs7527939

What is rs7527939?

rs7527939 is a single position in the genome, in or near the HHAT gene. Published research associates it with schizophrenia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7527939 linked to?

On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.

Does having rs7527939 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7527939 come from?

GWAS Catalog, Psychiatr Genet 2012, PMID:23142968. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Schizophrenia (rs7527939). MyGeneLog™. https://www.mygenelog.com/variants/rs7527939

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