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CD62L on CD62L+ Dendritic Cell

SELE · rs7526645

What the study found

Who was studied 2,871 Sardinian (founder/genetic isolate) ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.172 higher (95% confidence interval 0.12-0.22); p = 5 × 10−11.

How common The T allele had a frequency of about 46% in the people studied.

Where it sits Chromosome 1, band 1q24.2 — in an intron of SELE.

What each result means

C/C No copy of the version the research linked to CD62L on CD62L+ Dendritic Cell. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to CD62L on CD62L+ Dendritic Cell. That is a smaller link than two copies.
T/T Two copies of the version the research linked to CD62L on CD62L+ Dendritic Cell. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7526645

What is rs7526645?

rs7526645 is a single position in the genome, in or near the SELE gene. Published research associates it with cd62l on cd62l+ dendritic cell. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7526645 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7526645 come from?

GWAS Catalog, Nature genetics 2020, PMID:32929287. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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CD62L on CD62L+ Dendritic Cell (rs7526645). MyGeneLog™. https://www.mygenelog.com/variants/rs7526645

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