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Who was studied 133,492 European ancestry individuals.
The effect
The reported allele is G; the catalogue records no effect size
; p = 3 × 10−13.
How common The G allele had a frequency of about 93% in the people studied.
Where it sits Chromosome 16, band 16q23.1 — between genes, 46.8 kb from LINC02131.
What each result means
A/ANo copy of the version the research linked to Intraocular pressure. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Intraocular pressure. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Intraocular pressure. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs75265191 is a single position in the genome, in or near the ADAMTS18 gene. Published research associates it with intraocular pressure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75265191 linked to?
On MyGeneLog this position is linked to Intraocular Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs75265191 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75265191 come from?
GWAS Catalog, Nature genetics 2020, PMID:31959993. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 101522Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot5Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total10Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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