1 28321612418Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity0Meta AI6Microsoft · Copilot1Amazon2Apple4China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 8,344 Han Chinese ancestry individuals; replicated in 14,739 Han Chinese ancestry individuals.
The effect
Each copy of the T allele shifted the measure 2.21 higher (95% confidence interval 1.55-2.88); p = 2 × 10−10.
How common The T allele had a frequency of about 72% in the people studied.
Where it sits Chromosome 1, band 1p32.3 — between genes, 6 kb from PCSK9.
What each result means
C/CNo copy of the version the research linked to Cholesterol, total. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cholesterol, total. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cholesterol, total. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs7525649 is a single position in the genome, in or near the PCSK9 gene. Published research associates it with cholesterol, total. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7525649 linked to?
On MyGeneLog this position is linked to Cholesterol (LDL, HDL and Total). The research behind each link, and its sources, are set out on that condition page.
Does having rs7525649 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7525649 come from?
GWAS Catalog, Circ Cardiovasc Genet 2015, PMID:26582766. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 28321612418Reads by AI crawlersClaude3ChatGPT2Google · Gemini1Perplexity0Meta AI6Microsoft · Copilot1Amazon2Apple4China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others8Total28Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cholesterol, total (rs7525649). MyGeneLog™. https://www.mygenelog.com/variants/rs7525649