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Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms

LPA · rs75234242

Where this position leads

Condition: Lipoprotein(a) Levels

rs75234242 Condition: Lipoprotein(a) Levels Lipoprotein(a) Levels Condition rs75234242 rs75234242 LPA

What the study found

Who was studied 13,781 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 13.6 lower (95% confidence interval 12.18-15); p = 4 × 10−97.

Where it sits Chromosome 6, band 6q25.3 — in an intron of LPA.

What each result means

A/A Two copies of the version the research linked to Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms. That is a smaller link than two copies.
G/G No copy of the version the research linked to Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms. This is the starting point the study compared everyone against.
Source

Questions about rs75234242

What is rs75234242?

rs75234242 is a single position in the genome, in or near the LPA gene. Published research associates it with lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75234242 linked to?

On MyGeneLog this position is linked to Lipoprotein(a) Levels. The research behind each link, and its sources, are set out on that condition page.

Does having rs75234242 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75234242 come from?

GWAS Catalog, Journal of lipid research 2017, PMID:28512139. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Lipoprotein(a) levels adjusted for apolipoprotein(a) isoforms (rs75234242). MyGeneLog™. https://www.mygenelog.com/variants/rs75234242

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