Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis)
TNFSF18 · rs7521390
0 1512111Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 477,968 European ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.032 lower (95% confidence interval 0.022-0.042); p = 4 × 10−12.
How common The C allele had a frequency of about 30% in the people studied.
Where it sits Chromosome 1, band 1q25.1 — in the 3′ untranslated region of TNFSF4.
What each result means
A/ANo copy of the version the research linked to Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis). This is the starting point the study compared everyone against.
A/COne copy of the version the research linked to Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis). That is a smaller link than two copies.
C/CTwo copies of the version the research linked to Allergic disease (asthma, hay fever and/or eczema) (multivariate analysis). That is the strongest link of the three results. A link in a study is not a diagnosis.
PLoS genetics · 2020 · PMID 32603359 · open access
Questions about rs7521390
What is rs7521390?
rs7521390 is a single position in the genome, in or near the TNFSF18 gene. Published research associates it with allergic disease (asthma, hay fever and/or eczema) (multivariate analysis). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7521390 linked to?
On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.
Does having rs7521390 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7521390 come from?
GWAS Catalog, PLoS genetics 2020, PMID:32603359. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 1512111Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others11Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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