Standard

Glaucoma

LOC100147773 · rs7518099

Where this position leads

Condition: Glaucoma

rs7518099 Condition: Glaucoma Glaucoma Condition rs7518099 rs7518099 LOC100147773

What the study found

Who was studied 11,018 European ancestry cases, 126,068 European ancestry controls.

The effect Each copy of the T allele carried 1.37 times the odds of Glaucoma (95% confidence interval 1.32-1.43); p = 2 × 10−52.

Where it sits Chromosome 1, band 1q24.1 — in an intron of TMCO1.

What each result means

C/C No copy of the version the research linked to Glaucoma. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Glaucoma. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Glaucoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7518099

What is rs7518099?

rs7518099 is a single position in the genome, in or near the LOC100147773 gene. Published research associates it with glaucoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7518099 linked to?

On MyGeneLog this position is linked to Glaucoma. The research behind each link, and its sources, are set out on that condition page.

Does having rs7518099 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7518099 come from?

GWAS Catalog, Nat Genet 2018, PMID:30054594. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Glaucoma (rs7518099). MyGeneLog™. https://www.mygenelog.com/variants/rs7518099

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