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Serum creatinine levels

SUFU · rs75174967

What the study found

Who was studied 150,266 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0255 higher (95% confidence interval 0.018-0.033); p = 2 × 10−10.

How common The A allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 10, band 10q24.32 — in an intron of SUFU.

What each result means

A/A Two copies of the version the research linked to Serum creatinine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum creatinine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum creatinine levels. This is the starting point the study compared everyone against.
Source

Questions about rs75174967

What is rs75174967?

rs75174967 is a single position in the genome, in or near the SUFU gene. Published research associates it with serum creatinine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75174967 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75174967 come from?

GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum creatinine levels (rs75174967). MyGeneLog™. https://www.mygenelog.com/variants/rs75174967

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