Sex hormone-binding globulin levels adjusted for BMI
RNF212B · rs75170914
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 180,094 European ancestry men.
The effect
Each copy of the T allele shifted the measure 0.0125 higher (95% confidence interval 0.0099-0.0151); p = 5 × 10−26.
How common The T allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 14, band 14q11.2 — in an intron of RNF212B.
What each result means
C/CNo copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Sex hormone-binding globulin levels adjusted for BMI. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature medicine · 2020 · PMID 32042192 · open access
Questions about rs75170914
What is rs75170914?
rs75170914 is a single position in the genome, in or near the RNF212B gene. Published research associates it with sex hormone-binding globulin levels adjusted for bmi. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs75170914 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75170914 come from?
GWAS Catalog, Nature medicine 2020, PMID:32042192. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Sex hormone-binding globulin levels adjusted for BMI (rs75170914). MyGeneLog™. https://www.mygenelog.com/variants/rs75170914