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Thyroid stimulating hormone levels within normal range in pregnancy

VAV3 · rs75125154

What the study found

Who was studied 67,471 Chinese ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.114 higher (95% confidence interval 0.1-0.128); p = 3 × 10−56.

How common The G allele had a frequency of about 27% in the people studied.

Where it sits Chromosome 1, band 1p13.3 — in an intron of VAV3.

What each result means

A/A No copy of the version the research linked to Thyroid stimulating hormone levels within normal range in pregnancy. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Thyroid stimulating hormone levels within normal range in pregnancy. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Thyroid stimulating hormone levels within normal range in pregnancy. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75125154

What is rs75125154?

rs75125154 is a single position in the genome, in or near the VAV3 gene. Published research associates it with thyroid stimulating hormone levels within normal range in pregnancy. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75125154 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75125154 come from?

GWAS Catalog, Nature communications 2024, PMID:39266554. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Thyroid stimulating hormone levels within normal range in pregnancy (rs75125154). MyGeneLog™. https://www.mygenelog.com/variants/rs75125154

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