Standard

Low density lipoprotein cholesterol levels

near PPP1R3B · rs75120785

Where this position leads

Condition: Gout

rs75120785 Condition: Gout Gout Condition rs75120785 rs75120785 near PPP1R3B

What the study found

Who was studied 341,875 European ancestry individuals, 6,003 African ancestry individuals, 7,319 South Asian ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0239 higher (95% confidence interval 0.016-0.032); p = 2 × 10−9.

Where it sits Chromosome 8, band 8p23.1 — in an intron of PPP1R3B-DT.

What each result means

G/G Two copies of the version the research linked to Low density lipoprotein cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Low density lipoprotein cholesterol levels. That is a smaller link than two copies.
T/T No copy of the version the research linked to Low density lipoprotein cholesterol levels. This is the starting point the study compared everyone against.
Source

Questions about rs75120785

What is rs75120785?

rs75120785 is a single position in the genome, in or near the near PPP1R3B gene. Published research associates it with low density lipoprotein cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs75120785 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs75120785 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75120785 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Low density lipoprotein cholesterol levels (rs75120785). MyGeneLog™. https://www.mygenelog.com/variants/rs75120785

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