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Who was studied 31,787 European ancestry cases, 619,351 European ancestry controls.
The effect
Each copy of the T allele carried 1.05 times the odds of Basal cell carcinoma (95% confidence interval 1.03-1.06); p = 3 × 10−8.
How common The T allele had a frequency of about 61% in the people studied.
Where it sits Chromosome 19, band 19q13.33 — in an intron of SCAF1.
What each result means
A/ANo copy of the version the research linked to Basal cell carcinoma. This is the starting point the study compared everyone against.
A/TOne copy of the version the research linked to Basal cell carcinoma. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Basal cell carcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
Human molecular genetics · 2019 · PMID 31174203 · open access
Questions about rs7508601
What is rs7508601?
rs7508601 is a single position in the genome, in or near the SCAF1 gene. Published research associates it with basal cell carcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7508601 linked to?
On MyGeneLog this position is linked to Basal Cell Carcinoma. The research behind each link, and its sources, are set out on that condition page.
Does having rs7508601 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7508601 come from?
GWAS Catalog, Hum Mol Genet 2019, PMID:31174203. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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