1 372126123119Reads by AI crawlersClaude2ChatGPT0Google · Gemini1Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others19Total37Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 437 European ancestry individuals, 364 African American individuals, 453 Latino individuals, 674 Japanese American individuals, 311 Native Hawaiian ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.168 lower (95% confidence interval 0.11-0.23); p = 4 × 10−8.
Where it sits Chromosome 19, band 19q13.2 — in an intron of CYP2F2P.
What each result means
G/GNo copy of the version the research linked to Nicotine metabolite ratio in current smokers. This is the starting point the study compared everyone against.
G/TOne copy of the version the research linked to Nicotine metabolite ratio in current smokers. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Nicotine metabolite ratio in current smokers. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs7507400 is a single position in the genome, in or near the RAB4B-EGLN2 gene. Published research associates it with nicotine metabolite ratio in current smokers. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7507400 linked to?
On MyGeneLog this position is linked to Nicotine and Cotinine Metabolism. The research behind each link, and its sources, are set out on that condition page.
Does having rs7507400 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7507400 come from?
GWAS Catalog, Cancer Res 2016, PMID:27488534. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 372126123119Reads by AI crawlersClaude2ChatGPT0Google · Gemini1Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)1ByteDance (Doubao)1Others19Total37Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Nicotine metabolite ratio in current smokers (rs7507400). MyGeneLog™. https://www.mygenelog.com/variants/rs7507400