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Triglyceride to HDL cholesterol ratio

LINC00452 · rs75073260

What the study found

Who was studied 402,398 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0361 higher (95% confidence interval 0.029-0.043); p = 2 × 10−15.

How common The T allele had a frequency of about 86% in the people studied.

Where it sits Chromosome 13, band 13q34 — in an intron of LINC00452.

What each result means

G/G No copy of the version the research linked to Triglyceride to HDL cholesterol ratio. This is the starting point the study compared everyone against.
G/T One copy of the version the research linked to Triglyceride to HDL cholesterol ratio. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Triglyceride to HDL cholesterol ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs75073260

What is rs75073260?

rs75073260 is a single position in the genome, in or near the LINC00452 gene. Published research associates it with triglyceride to hdl cholesterol ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75073260 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75073260 come from?

GWAS Catalog, Nature genetics 2024, PMID:38200128. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride to HDL cholesterol ratio (rs75073260). MyGeneLog™. https://www.mygenelog.com/variants/rs75073260

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