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MSR1 protein levels

ST3GAL4 · rs75071241

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.185 lower (95% confidence interval 0.16-0.21); p = 6 × 10⁻⁷⁴.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 11, band 11q24.2 — in an intron of ST3GAL4.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of MSR1 protein levels compared to the general population.

A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with MSR1 protein levels.

G/G Published research associates this genotype with typical/baseline likelihood of MSR1 protein levels — no copies of the reported risk allele.

Source

A scalable variational inference approach for increased mixed-model association power

Loya H, Kalantzis G, Cooper F, Palamara PF

Nature genetics · 2025 · PMID 39789286 · open access

Questions about rs75071241

What is rs75071241?

rs75071241 is a single position in the genome, in or near the ST3GAL4 gene. Published research associates it with msr1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs75071241 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs75071241 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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MSR1 protein levels (rs75071241). MyGeneLog™. https://www.mygenelog.com/variants/rs75071241

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