Type 2 diabetes and end-stage kidney disease in APOL1 risk genotype negative individuals
GRAMD3 · rs75029938
0 413Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others3Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 2,768 African-American cases, 6,059 African-American controls.
The effect
Each copy of the T allele carried 1.89 times the odds of Type 2 diabetes and end-stage kidney disease in APOL1 risk genotype negative individuals (95% confidence interval 1.54-2.34); p = 2 × 10−9.
How common The T allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 5, band 5q23.2 — in an intron of GRAMD2B.
What each result means
C/CNo copy of the version the research linked to Type 2 diabetes and end-stage kidney disease in APOL1 risk genotype negative individuals. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Type 2 diabetes and end-stage kidney disease in APOL1 risk genotype negative individuals. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Type 2 diabetes and end-stage kidney disease in APOL1 risk genotype negative individuals. That is the strongest link of the three results. A link in a study is not a diagnosis.
Human genomics · 2019 · PMID 31092297 · open access
Questions about rs75029938
What is rs75029938?
rs75029938 is a single position in the genome, in or near the GRAMD3 gene. Published research associates it with type 2 diabetes and end-stage kidney disease in apol1 risk genotype negative individuals. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs75029938 linked to?
On MyGeneLog this position is linked to Type 2 Diabetes. The research behind each link, and its sources, are set out on that condition page.
Does having rs75029938 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs75029938 come from?
GWAS Catalog, Human genomics 2019, PMID:31092297. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 413Reads by AI crawlersClaude1ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others3Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Type 2 diabetes and end-stage kidney disease in APOL1 risk genotype negative individuals (rs75029938). MyGeneLog™. https://www.mygenelog.com/variants/rs75029938