Beta-carotene to vitamin A conversion efficiency (BCO1 A379V)
BCO1 · rs7501331
1 38426123218Reads by AI crawlersClaude0ChatGPT0Google · Gemini4Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others18Total38Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
ClassificationBenign for Malignant lymphoma, large B-cell, diffuse, Uterine carcinosarcoma; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2021-06-09.
ClinVar record 1253021NM_017429.3(BCO1):c.1136C>T (p.Ala379Val)
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the 379V variant. Typical BCO1 conversion efficiency in the discovery study.
C/TCarries one copy of the 379V variant. In the discovery study, carriers of at least one copy (this genotype and T/T combined) converted beta-carotene to vitamin A 32% less efficiently (P=0.005) and had 160% higher fasting beta-carotene levels than non-carriers.
T/TCarries two copies of the 379V variant. The discovery study reported carriers of at least one copy (this genotype and C/T combined) as 32% less efficient converters; it did not report a separate figure for two copies versus one.
Talk to a doctor or a registered dietitian about vitamin A sources, especially if you rely mainly on plant foods for it.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2009 · PMID 19103647
Questions about rs7501331
What is rs7501331?
rs7501331 is a single position in the genome, in or near the BCO1 gene. Published research associates it with beta-carotene to vitamin a conversion efficiency (bco1 a379v). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7501331 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7501331 come from?
Leung et al. 2009, FASEB Journal — two common SNPs in BCO1 alter beta-carotene metabolism in female volunteers. PMID 19103647. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 38426123218Reads by AI crawlersClaude0ChatGPT0Google · Gemini4Perplexity2Meta AI6Microsoft · Copilot1Amazon2Apple3China (ByteDance, Huawei, Baidu…)2ByteDance (Doubao)2Others18Total38Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Beta-carotene to vitamin A conversion efficiency (BCO1 A379V) (rs7501331). MyGeneLog™. https://www.mygenelog.com/variants/rs7501331