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Non-HDL cholesterol levels

near PDE4A · rs74937111

What the study found

Who was studied 99,432 Admixed African or African ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.258 lower (95% confidence interval 0.2-0.32); p = 3 × 10−16.

How common The T allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — between genes, 4 kb from PDE4A.

What each result means

A/A No copy of the version the research linked to Non-HDL cholesterol levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Non-HDL cholesterol levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Non-HDL cholesterol levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs74937111

What is rs74937111?

rs74937111 is a single position in the genome, in or near the near PDE4A gene. Published research associates it with non-hdl cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74937111 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74937111 come from?

GWAS Catalog, Nature 2021, PMID:34887591. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Non-HDL cholesterol levels (rs74937111). MyGeneLog™. https://www.mygenelog.com/variants/rs74937111

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