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PCDH17 protein levels

near RNU7-88P · rs74932030

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.276 lower (95% confidence interval 0.23-0.32); p = 8 × 10−39.

How common The G allele had a frequency of about 2% in the people studied.

Where it sits Chromosome 13, band 13q21.2 — between genes, 87.6 kb from RNU7-88P.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of PCDH17 protein levels — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with PCDH17 protein levels.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of PCDH17 protein levels compared to the general population.
Source

Questions about rs74932030

What is rs74932030?

rs74932030 is a single position in the genome, in or near the near RNU7-88P gene. Published research associates it with pcdh17 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74932030 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74932030 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

PCDH17 protein levels (rs74932030). MyGeneLog™. https://www.mygenelog.com/variants/rs74932030

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