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Who was studied 39,397 British ancestry blond hair individuals, 283,920 British ancestry brown or black hair individuals.
The effect
The reported allele is C; the catalogue records no effect size
; p = 2 × 10−10.
How common The C allele had a frequency of about 7% in the people studied.
Where it sits Chromosome 12, band 12q21.32 — between genes, 81 kb from TMTC3.
What each result means
C/CTwo copies of the version the research linked to Blond vs. brown/black hair color. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Blond vs. brown/black hair color. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Blond vs. brown/black hair color. This is the starting point the study compared everyone against.
Nature communications · 2018 · PMID 30531825 · open access
Questions about rs7487365
What is rs7487365?
rs7487365 is a single position in the genome, in or near the TMTC3 gene. Published research associates it with blond vs. brown/black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7487365 linked to?
On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.
Does having rs7487365 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7487365 come from?
GWAS Catalog, Nature communications 2018, PMID:30531825. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Blond vs. brown/black hair color (rs7487365). MyGeneLog™. https://www.mygenelog.com/variants/rs7487365