0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 342,399 European ancestry individuals, 6,015 African ancestry individuals, 7,338 South Asian ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.0696 higher (95% confidence interval 0.05-0.089); p = 2 × 10−12.
Where it sits Chromosome 20, band 20p11.21 — in an intron of ZNF337.
What each result means
A/ATwo copies of the version the research linked to Cystatin C levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Cystatin C levels. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Cystatin C levels. This is the starting point the study compared everyone against.
Nature genetics · 2021 · PMID 33462484 · open access
Questions about rs74853405
What is rs74853405?
rs74853405 is a single position in the genome, in or near the ZNF337 gene. Published research associates it with cystatin c levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs74853405 linked to?
On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.
Does having rs74853405 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74853405 come from?
GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Cystatin C levels (rs74853405). MyGeneLog™. https://www.mygenelog.com/variants/rs74853405