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Sex hormone-binding globulin levels

R3HDM2 · rs7484541

What the study found

Who was studied 196,901 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0371 higher (95% confidence interval 0.03-0.045); p = 1 × 10−22.

How common The T allele had a frequency of about 22% in the people studied.

Where it sits Chromosome 12, band 12q13.3 — in an intron of R3HDM2.

What each result means

A/A No copy of the version the research linked to Sex hormone-binding globulin levels. This is the starting point the study compared everyone against.
A/T One copy of the version the research linked to Sex hormone-binding globulin levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Sex hormone-binding globulin levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7484541

What is rs7484541?

rs7484541 is a single position in the genome, in or near the R3HDM2 gene. Published research associates it with sex hormone-binding globulin levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7484541 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7484541 come from?

GWAS Catalog, Endocrinology 2022, PMID:35192695. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sex hormone-binding globulin levels (rs7484541). MyGeneLog™. https://www.mygenelog.com/variants/rs7484541

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