Standard

OLR1 protein levels

near OR5BE1P · rs74799799

Where this position leads

Condition: Celiac Disease

rs74799799 Condition: Celiac Disease Celiac Disease Condition rs74799799 rs74799799 near OR5BE1P

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0903 lower (95% confidence interval 0.062-0.118); p = 1 × 10−11.

How common The T allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 11, band 11q12.1 — between genes, 0.7 kb from OR5BE1P.

What each result means

C/C No copy of the version the research linked to OLR1 protein levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to OLR1 protein levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to OLR1 protein levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs74799799

What is rs74799799?

rs74799799 is a single position in the genome, in or near the near OR5BE1P gene. Published research associates it with olr1 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs74799799 linked to?

On MyGeneLog this position is linked to Celiac Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs74799799 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74799799 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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OLR1 protein levels (rs74799799). MyGeneLog™. https://www.mygenelog.com/variants/rs74799799

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