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Cholesteryl Esters to Total Lipids in Medium VLDL percentage

RRAS2 · rs74749286

What the study found

Who was studied 241,027 British ancestry females.

The effect Each copy of the A allele shifted the measure 0.0352 % higher (95% confidence interval 0.026-0.044); p = 3 × 10−15.

Where it sits Chromosome 11, band 11p15.2 — in an intron of RRAS2.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Cholesteryl Esters to Total Lipids in Medium VLDL percentage compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Cholesteryl Esters to Total Lipids in Medium VLDL percentage.
G/G Published research associates this genotype with typical/baseline likelihood of Cholesteryl Esters to Total Lipids in Medium VLDL percentage — no copies of the reported risk allele.
Source

Questions about rs74749286

What is rs74749286?

rs74749286 is a single position in the genome, in or near the RRAS2 gene. Published research associates it with cholesteryl esters to total lipids in medium vldl percentage. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74749286 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74749286 come from?

GWAS Catalog, Nature genetics 2025, PMID:41044249. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Cholesteryl Esters to Total Lipids in Medium VLDL percentage (rs74749286). MyGeneLog™. https://www.mygenelog.com/variants/rs74749286

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