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Hippocampus iron levels (quantitative susceptibility mapping)

KIF18B · rs74732746

What the study found

Who was studied 39,533 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.13 lower (95% confidence interval 0.099-0.162); p = 1 × 10−15.

Where it sits Chromosome 17, band 17q21.31 — in an intron of KIF18B.

What each result means

C/C Two copies of the version the research linked to Hippocampus iron levels (quantitative susceptibility mapping). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Hippocampus iron levels (quantitative susceptibility mapping). That is a smaller link than two copies.
T/T No copy of the version the research linked to Hippocampus iron levels (quantitative susceptibility mapping). This is the starting point the study compared everyone against.
Source

Questions about rs74732746

What is rs74732746?

rs74732746 is a single position in the genome, in or near the KIF18B gene. Published research associates it with hippocampus iron levels (quantitative susceptibility mapping). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74732746 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74732746 come from?

GWAS Catalog, Neurobiology of disease 2024, PMID:38789058. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hippocampus iron levels (quantitative susceptibility mapping) (rs74732746). MyGeneLog™. https://www.mygenelog.com/variants/rs74732746

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