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Chlamydia trachomatis PorB antibody levels

TP63 · rs74725117

What the study found

Who was studied 273 White British ancestry individuals.

The effect Each copy of the T allele shifted the measure 1.71 lower (95% confidence interval 1.12-2.30); p = 5 × 10−8.

How common The T allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 3, band 3q28 — between genes, 90.9 kb from TP63.

What each result means

G/G Published research associates this genotype with typical/baseline likelihood of Chlamydia trachomatis PorB antibody levels — no copies of the reported risk allele.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Chlamydia trachomatis PorB antibody levels.
T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Chlamydia trachomatis PorB antibody levels compared to the general population.
Source

Questions about rs74725117

What is rs74725117?

rs74725117 is a single position in the genome, in or near the TP63 gene. Published research associates it with chlamydia trachomatis porb antibody levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74725117 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74725117 come from?

GWAS Catalog, Open Forum Infect Dis 2020, PMID:33204752. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Chlamydia trachomatis PorB antibody levels (rs74725117). MyGeneLog™. https://www.mygenelog.com/variants/rs74725117

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