Sensitive

1,4-dihydro-1-Methyl-4-oxo-3-pyridinecarboxamide levels in coronary artery disease

PWP2 · rs74716564

Where this position leads

Condition: Coronary Artery Disease

rs74716564 Condition: Coronary Artery Disease Coronary Artery Disease Condition rs74716564 rs74716564 PWP2

What the study found

Who was studied 1,551 Han Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.47 lower (95% confidence interval 0.33-0.61); p = 6 × 10−11.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 21, band 21q22.3 — in an intron of PWP2.

What each result means

A/A Two copies of the version the research linked to 1,4-dihydro-1-Methyl-4-oxo-3-pyridinecarboxamide levels in coronary artery disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to 1,4-dihydro-1-Methyl-4-oxo-3-pyridinecarboxamide levels in coronary artery disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to 1,4-dihydro-1-Methyl-4-oxo-3-pyridinecarboxamide levels in coronary artery disease. This is the starting point the study compared everyone against.
Source

Questions about rs74716564

What is rs74716564?

rs74716564 is a single position in the genome, in or near the PWP2 gene. Published research associates it with 1,4-dihydro-1-methyl-4-oxo-3-pyridinecarboxamide levels in coronary artery disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs74716564 linked to?

On MyGeneLog this position is linked to Coronary Artery Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs74716564 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74716564 come from?

GWAS Catalog, Clinical and translational medicine 2021, PMID:33634981. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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1,4-dihydro-1-Methyl-4-oxo-3-pyridinecarboxamide levels in coronary artery disease (rs74716564). MyGeneLog™. https://www.mygenelog.com/variants/rs74716564

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