Standard

Blood glucose levels

RMST · rs74628648

Where this position leads

Condition: Gout

rs74628648 Condition: Gout Gout Condition rs74628648 rs74628648 RMST

What the study found

Who was studied 313,125 European ancestry individuals, 5,568 African ancestry individuals, 6,693 South Asian ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.0429 lower (95% confidence interval 0.032-0.053); p = 2 × 10−15.

Where it sits Chromosome 12, band 12q23.1 — inside RMST.

What each result means

C/C No copy of the version the research linked to Blood glucose levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Blood glucose levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Blood glucose levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs74628648

What is rs74628648?

rs74628648 is a single position in the genome, in or near the RMST gene. Published research associates it with blood glucose levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs74628648 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs74628648 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74628648 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blood glucose levels (rs74628648). MyGeneLog™. https://www.mygenelog.com/variants/rs74628648

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