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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 6,057 European ancestry individuals.
The effect
The reported allele is T; the catalogue records no effect size
; p = 1 × 10−11.
Where it sits Chromosome 3, band 3q27.3 — in an intron of ST6GAL1.
What each result means
C/CNo copy of the version the research linked to GM1 ganglioside (d18:1/16:0) levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to GM1 ganglioside (d18:1/16:0) levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to GM1 ganglioside (d18:1/16:0) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2022 · PMID 35668104 · open access
Questions about rs74618283
What is rs74618283?
rs74618283 is a single position in the genome, in or near the ST6GAL1 gene. Published research associates it with gm1 ganglioside (d18:1/16:0) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs74618283 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74618283 come from?
GWAS Catalog, Nature communications 2022, PMID:35668104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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