A/APublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Childhood onset systemic lupus erythematosus compared to the general population.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Childhood onset systemic lupus erythematosus.
G/GPublished research associates this genotype with typical/baseline likelihood of Childhood onset systemic lupus erythematosus — no copies of the reported risk allele.
Scientific reports · 2018 · PMID 29967481 · open access
Questions about rs7460469
What is rs7460469?
rs7460469 is a single position in the genome, in or near the XKR6 gene. Published research associates it with childhood onset systemic lupus erythematosus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7460469 linked to?
On MyGeneLog this position is linked to Systemic Lupus Erythematosus. The research behind each link, and its sources, are set out on that condition page.
Does having rs7460469 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7460469 come from?
GWAS Catalog, Sci Rep 2018, PMID:29967481. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.