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Phosphatidylcholine levels

FADS2 · rs74556176

What the study found

Who was studied 2,045 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.444 lower (95% confidence interval 0.31-0.57); p = 4 × 10−11.

Where it sits Chromosome 11, band 11q12.3 — between genes, 5.1 kb from RNU6-1243P.

What each result means

A/A Two copies of the version the research linked to Phosphatidylcholine levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Phosphatidylcholine levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Phosphatidylcholine levels. This is the starting point the study compared everyone against.
Source

Questions about rs74556176

What is rs74556176?

rs74556176 is a single position in the genome, in or near the FADS2 gene. Published research associates it with phosphatidylcholine levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74556176 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74556176 come from?

GWAS Catalog, Nature communications 2019, PMID:31551469. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Phosphatidylcholine levels (rs74556176). MyGeneLog™. https://www.mygenelog.com/variants/rs74556176

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