Schizophrenia or ER positive breast cancer (pleiotropy)
near HCN1 · rs7447717
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 53,386 European ancestry schizophrenia cases, 69,501 European ancestry ER positive breast cancer cases, 183,232 European ancestry controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 8 × 10−16.
Where it sits Chromosome 5, band 5p12 — between genes, 73.7 kb from HCN1.
What each result means
A/ATwo copies of the version the research linked to Schizophrenia or ER positive breast cancer (pleiotropy). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Schizophrenia or ER positive breast cancer (pleiotropy). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Schizophrenia or ER positive breast cancer (pleiotropy). This is the starting point the study compared everyone against.
rs7447717 is a single position in the genome, in or near the near HCN1 gene. Published research associates it with schizophrenia or er positive breast cancer (pleiotropy). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7447717 linked to?
On MyGeneLog this position is linked to Schizophrenia. The research behind each link, and its sources, are set out on that condition page.
Does having rs7447717 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7447717 come from?
GWAS Catalog, Schizophrenia bulletin 2024, PMID:37467357. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Schizophrenia or ER positive breast cancer (pleiotropy) (rs7447717). MyGeneLog™. https://www.mygenelog.com/variants/rs7447717