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Alcohol and nicotine co-dependence

HTR1A · rs7445832

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Alcohol and nicotine co-dependence compared to the general population.

A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Alcohol and nicotine co-dependence.

T/T Published research associates this genotype with typical/baseline likelihood of Alcohol and nicotine co-dependence — no copies of the reported risk allele.

Source

Genome-wide significant association signals in IPO11-HTR1A region specific for alcohol and nicotine codependence

Zuo L, Zhang XY, Wang F, Li CS, Lu L, Ye L, Zhang H, Krystal JH, Deng HW, Luo X

Alcoholism, clinical and experimental research · 2013 · PMID 23216389

Questions about rs7445832

What is rs7445832?

rs7445832 is a single position in the genome, in or near the HTR1A gene. Published research associates it with alcohol and nicotine co-dependence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7445832 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7445832 come from?

GWAS Catalog, Alcohol Clin Exp Res 2012, PMID:23216389. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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