HTR1A · rs7445832
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 818 European ancestry cases, 1,396 European ancestry controls; replicated in Up to 907 European ancestry cases, up to 2,830 European ancestry controls, up to 449 African American cases, up to 480 African American controls.
The effect Each copy of the A allele carried 1.15 times the odds of Alcohol and nicotine co-dependence; p = 1 × 10−9.
Where it sits Chromosome 5, band 5q12.1 — between genes, 11 kb from LOC100420027.
What people read about alongside this
Papers in Europe PMC whose title or abstract names both this rsID and that subject. A shared paper means somebody wrote about the two together — it is not a claim that this position explains the subject.
rs7445832 is a single position in the genome, in or near the HTR1A gene. Published research associates it with alcohol and nicotine co-dependence. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Subjects that appear in the title or abstract of the same papers as this rsID include alcohol and the flush (1 papers). A shared paper means somebody wrote about the two together; it is not a claim that this position explains the topic.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Alcohol Clin Exp Res 2012, PMID:23216389. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Alcohol and nicotine co-dependence (rs7445832). MyGeneLog™. https://www.mygenelog.com/variants/rs7445832