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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 7,058 Chinese Han ancestry individuals.
The effect
Each copy of the C allele shifted the measure 0.379 higher (95% confidence interval 0.26-0.5); p = 8 × 10−10.
Where it sits Chromosome 1, band 1q32.2 — between genes, 10.9 kb from LINC01698.
What each result means
C/CTwo copies of the version the research linked to T1 FreeSurfer DKT rh insula area. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to T1 FreeSurfer DKT rh insula area. That is a smaller link than two copies.
T/TNo copy of the version the research linked to T1 FreeSurfer DKT rh insula area. This is the starting point the study compared everyone against.
rs74443991 is a single position in the genome, in or near the near LINC01698 gene. Published research associates it with t1 freesurfer dkt rh insula area. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs74443991 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74443991 come from?
GWAS Catalog, Nature genetics 2024, PMID:38811844. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
T1 FreeSurfer DKT rh insula area (rs74443991). MyGeneLog™. https://www.mygenelog.com/variants/rs74443991