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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 39,313 European ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.168 SD units higher (95% confidence interval 0.12-0.21); p = 7 × 10−13.
How common The A allele had a frequency of about 2% in the people studied.
Where it sits Chromosome 10, band 10q11.22 — a missense change in ZFAND4.
What each result means
A/ATwo copies of the version the research linked to Red cell distribution width - standard deviation. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Red cell distribution width - standard deviation. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Red cell distribution width - standard deviation. This is the starting point the study compared everyone against.
Nature communications · 2023 · PMID 37596262 · open access
Questions about rs74436700
What is rs74436700?
rs74436700 is a single position in the genome, in or near the ZFAND4 gene. Published research associates it with red cell distribution width - standard deviation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs74436700 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74436700 come from?
GWAS Catalog, Nature communications 2023, PMID:37596262. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Red cell distribution width - standard deviation (rs74436700). MyGeneLog™. https://www.mygenelog.com/variants/rs74436700