Standard

Insomnia

near RPL7P13 · rs74431276

Where this position leads

Condition: Insomnia

rs74431276 Condition: Insomnia Insomnia Condition rs74431276 rs74431276 near RPL7P13

What the study found

Who was studied 593,724 European ancestry cases, 1,771,286 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.01 higher (95% confidence interval 0.008-0.012); p = 5 × 10−11.

Where it sits Chromosome 2, band 2p16.3 — between genes, 5.2 kb from RPL7P13.

What each result means

A/A Two copies of the version the research linked to Insomnia. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Insomnia. That is a smaller link than two copies.
G/G No copy of the version the research linked to Insomnia. This is the starting point the study compared everyone against.
Source

Questions about rs74431276

What is rs74431276?

rs74431276 is a single position in the genome, in or near the near RPL7P13 gene. Published research associates it with insomnia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs74431276 linked to?

On MyGeneLog this position is linked to Insomnia. The research behind each link, and its sources, are set out on that condition page.

Does having rs74431276 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74431276 come from?

GWAS Catalog, Nature genetics 2022, PMID:35835914. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Insomnia (rs74431276). MyGeneLog™. https://www.mygenelog.com/variants/rs74431276

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