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Who was studied 362,661 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 8.03 z score higher; p = 1 × 10−15.
Where it sits Chromosome 11, band 11q24.3 — in an intron of KCNJ5-AS1.
What each result means
C/CNo copy of the version the research linked to Cardioembolic stroke (MTAG). This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Cardioembolic stroke (MTAG). That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Cardioembolic stroke (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
Frontiers in cardiovascular medicine · 2022 · PMID 35872910 · open access
Questions about rs74399915
What is rs74399915?
rs74399915 is a single position in the genome, in or near the KCNJ5-AS1 gene. Published research associates it with cardioembolic stroke (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs74399915 linked to?
On MyGeneLog this position is linked to Cardioembolic Stroke. The research behind each link, and its sources, are set out on that condition page.
Does having rs74399915 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs74399915 come from?
GWAS Catalog, Frontiers in cardiovascular medicine 2022, PMID:35872910. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
1 1513722Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot7Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total15Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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