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Appendicular lean mass

XKR7 · rs74397018

What the study found

Who was studied 450,243 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0321 lower (95% confidence interval 0.023-0.041); p = 1 × 10−11.

How common The A allele had a frequency of about 4% in the people studied.

Where it sits Chromosome 20, band 20q11.21 — in an intron of XKR7.

What each result means

A/A Two copies of the version the research linked to Appendicular lean mass. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Appendicular lean mass. That is a smaller link than two copies.
G/G No copy of the version the research linked to Appendicular lean mass. This is the starting point the study compared everyone against.
Source

Questions about rs74397018

What is rs74397018?

rs74397018 is a single position in the genome, in or near the XKR7 gene. Published research associates it with appendicular lean mass. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs74397018 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs74397018 come from?

GWAS Catalog, Communications biology 2020, PMID:33097823. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Appendicular lean mass (rs74397018). MyGeneLog™. https://www.mygenelog.com/variants/rs74397018

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