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Hemoglobin concentration

near XXYLT1 · rs7428617

What the study found

Who was studied 46,904 European ancestry males; replicated in 80,822 European ancestry males.

The effect Each copy of the A allele shifted the measure 0.0261 higher; p = 3 × 10−12.

How common The A allele had a frequency of about 49% in the people studied.

Where it sits Chromosome 3, band 3q29 — between genes, 109.9 kb from XXYLT1.

What each result means

A/A Two copies of the version the research linked to Hemoglobin concentration. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Hemoglobin concentration. That is a smaller link than two copies.
G/G No copy of the version the research linked to Hemoglobin concentration. This is the starting point the study compared everyone against.
Source

Questions about rs7428617

What is rs7428617?

rs7428617 is a single position in the genome, in or near the near XXYLT1 gene. Published research associates it with hemoglobin concentration. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7428617 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7428617 come from?

GWAS Catalog, The Journal of nutritional biochemistry 2023, PMID:35964923. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Hemoglobin concentration (rs7428617). MyGeneLog™. https://www.mygenelog.com/variants/rs7428617

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